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Flash Memory: Photochemical Imprinting of Neuronal Action Potentials onto a Microbial Rhodopsin
[Image: see text] We developed a technique, “flash memory”, to record a photochemical imprint of the activity state—firing or not firing—of a neuron at a user-selected moment in time. The key element is an engineered microbial rhodopsin protein with three states. Two nonfluorescent states, D(1) and...
Autores principales: | Venkatachalam, Veena, Brinks, Daan, Maclaurin, Dougal, Hochbaum, Daniel, Kralj, Joel, Cohen, Adam E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985752/ https://www.ncbi.nlm.nih.gov/pubmed/24428326 http://dx.doi.org/10.1021/ja411338t |
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