Cargando…

Structure and Function of the Genomically Encoded Fosfomycin Resistance Enzyme, FosB, from Staphylococcus aureus

[Image: see text] The Gram-positive pathogen Staphylococcus aureus is a leading cause of global morbidity and mortality. Like many multi-drug-resistant organisms, S. aureus contains antibiotic-modifying enzymes that facilitate resistance to a multitude of antimicrobial compounds. FosB is a Mn(2+)-de...

Descripción completa

Detalles Bibliográficos
Autores principales: Thompson, Matthew K., Keithly, Mary E., Goodman, Michael C., Hammer, Neal D., Cook, Paul D., Jagessar, Kevin L., Harp, Joel, Skaar, Eric P., Armstrong, Richard N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985756/
https://www.ncbi.nlm.nih.gov/pubmed/24447055
http://dx.doi.org/10.1021/bi4015852