Structure Based Design, Synthesis, Pharmacophore Modeling, Virtual Screening, and Molecular Docking Studies for Identification of Novel Cyclophilin D Inhibitors

[Image: see text] Cyclophilin D (CypD) is a peptidyl prolyl isomerase F that resides in the mitochondrial matrix and associates with the inner mitochondrial membrane during the mitochondrial membrane permeability transition. CypD plays a central role in opening the mitochondrial membrane permeabilit...

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Detalles Bibliográficos
Autores principales: Valasani, Koteswara Rao, Vangavaragu, Jhansi Rani, Day, Victor W., Yan, Shirley ShiDu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985759/
https://www.ncbi.nlm.nih.gov/pubmed/24555519
http://dx.doi.org/10.1021/ci5000196

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985759/
https://www.ncbi.nlm.nih.gov/pubmed/24555519
http://dx.doi.org/10.1021/ci5000196

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