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Intracranial Metastasis in a Patient with Hepatocellular Carcinoma and Gastric Cancer

A 76-year-old man was referred to our hospital with visual disturbance, weakness of the left upper and lower limbs, and gait disturbance. He had previously received transarterial chemoembolization for hepatocellular carcinoma (HCC) 3 and 10 years ago. When he had received radiofrequency ablation for...

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Autores principales: Tawada, Akinobu, Chiba, Tetsuhiro, Ooka, Yoshihiko, Yokota, Hajime, Kanogawa, Naoya, Motoyama, Tenyu, Saito, Tomoko, Ogasawara, Sadahisa, Suzuki, Eiichiro, Hanari, Naoyuki, Matsubara, Hisahiro, Saeki, Naokatsu, Kambe, Michiyo, Kishimoto, Takashi, Nakatani, Yukio, Yokosuka, Osamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985793/
https://www.ncbi.nlm.nih.gov/pubmed/24748871
http://dx.doi.org/10.1159/000360982
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author Tawada, Akinobu
Chiba, Tetsuhiro
Ooka, Yoshihiko
Yokota, Hajime
Kanogawa, Naoya
Motoyama, Tenyu
Saito, Tomoko
Ogasawara, Sadahisa
Suzuki, Eiichiro
Hanari, Naoyuki
Matsubara, Hisahiro
Saeki, Naokatsu
Kambe, Michiyo
Kishimoto, Takashi
Nakatani, Yukio
Yokosuka, Osamu
author_facet Tawada, Akinobu
Chiba, Tetsuhiro
Ooka, Yoshihiko
Yokota, Hajime
Kanogawa, Naoya
Motoyama, Tenyu
Saito, Tomoko
Ogasawara, Sadahisa
Suzuki, Eiichiro
Hanari, Naoyuki
Matsubara, Hisahiro
Saeki, Naokatsu
Kambe, Michiyo
Kishimoto, Takashi
Nakatani, Yukio
Yokosuka, Osamu
author_sort Tawada, Akinobu
collection PubMed
description A 76-year-old man was referred to our hospital with visual disturbance, weakness of the left upper and lower limbs, and gait disturbance. He had previously received transarterial chemoembolization for hepatocellular carcinoma (HCC) 3 and 10 years ago. When he had received radiofrequency ablation for HCC recurrence 2 years ago, total gastrectomy was also performed for his gastric cancer. Subsequently, sorafenib had been administrated for concomitant lung metastatic tumors. On admission, MRI revealed an intra-axial tumor with perifocal edema. The level of carcinoembryonic antigen, but not alpha-fetoprotein, markedly increased. The tumor was successfully removed by craniotomy and pathological examination revealed that it was composed of adenocarcinoma, which was consistent with the primary gastric cancer. After surgery, his neurological disturbances rapidly resolved. Additional gamma-knife treatment was also performed for another small brain metastasis detected after craniotomy. Subsequently, sorafenib administration was discontinued and S-1 was administered postoperatively. Successful treatment of intracranial metastasis of gastric cancer is important and meaningful, even in patients with multiple primary malignancies.
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spelling pubmed-39857932014-04-18 Intracranial Metastasis in a Patient with Hepatocellular Carcinoma and Gastric Cancer Tawada, Akinobu Chiba, Tetsuhiro Ooka, Yoshihiko Yokota, Hajime Kanogawa, Naoya Motoyama, Tenyu Saito, Tomoko Ogasawara, Sadahisa Suzuki, Eiichiro Hanari, Naoyuki Matsubara, Hisahiro Saeki, Naokatsu Kambe, Michiyo Kishimoto, Takashi Nakatani, Yukio Yokosuka, Osamu Case Rep Oncol Published online: March, 2014 A 76-year-old man was referred to our hospital with visual disturbance, weakness of the left upper and lower limbs, and gait disturbance. He had previously received transarterial chemoembolization for hepatocellular carcinoma (HCC) 3 and 10 years ago. When he had received radiofrequency ablation for HCC recurrence 2 years ago, total gastrectomy was also performed for his gastric cancer. Subsequently, sorafenib had been administrated for concomitant lung metastatic tumors. On admission, MRI revealed an intra-axial tumor with perifocal edema. The level of carcinoembryonic antigen, but not alpha-fetoprotein, markedly increased. The tumor was successfully removed by craniotomy and pathological examination revealed that it was composed of adenocarcinoma, which was consistent with the primary gastric cancer. After surgery, his neurological disturbances rapidly resolved. Additional gamma-knife treatment was also performed for another small brain metastasis detected after craniotomy. Subsequently, sorafenib administration was discontinued and S-1 was administered postoperatively. Successful treatment of intracranial metastasis of gastric cancer is important and meaningful, even in patients with multiple primary malignancies. S. Karger AG 2014-03-14 /pmc/articles/PMC3985793/ /pubmed/24748871 http://dx.doi.org/10.1159/000360982 Text en Copyright © 2014 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article licensed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported license (CC BY-NC) (www.karger.com/OA-license), applicable to the online version of the article only. Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions.
spellingShingle Published online: March, 2014
Tawada, Akinobu
Chiba, Tetsuhiro
Ooka, Yoshihiko
Yokota, Hajime
Kanogawa, Naoya
Motoyama, Tenyu
Saito, Tomoko
Ogasawara, Sadahisa
Suzuki, Eiichiro
Hanari, Naoyuki
Matsubara, Hisahiro
Saeki, Naokatsu
Kambe, Michiyo
Kishimoto, Takashi
Nakatani, Yukio
Yokosuka, Osamu
Intracranial Metastasis in a Patient with Hepatocellular Carcinoma and Gastric Cancer
title Intracranial Metastasis in a Patient with Hepatocellular Carcinoma and Gastric Cancer
title_full Intracranial Metastasis in a Patient with Hepatocellular Carcinoma and Gastric Cancer
title_fullStr Intracranial Metastasis in a Patient with Hepatocellular Carcinoma and Gastric Cancer
title_full_unstemmed Intracranial Metastasis in a Patient with Hepatocellular Carcinoma and Gastric Cancer
title_short Intracranial Metastasis in a Patient with Hepatocellular Carcinoma and Gastric Cancer
title_sort intracranial metastasis in a patient with hepatocellular carcinoma and gastric cancer
topic Published online: March, 2014
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985793/
https://www.ncbi.nlm.nih.gov/pubmed/24748871
http://dx.doi.org/10.1159/000360982
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