Cargando…

Two-Phase Synthesis of (−)-Taxuyunnanine D

[Image: see text] The first successful effort to replicate the beginning of the Taxol oxidase phase in the laboratory is reported, culminating in the total synthesis of taxuyunnanine D, itself a natural product. Through a combination of computational modeling, reagent screening, and oxidation sequen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wilde, Nathan C., Isomura, Minetaka, Mendoza, Abraham, Baran, Phil S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985808/ https://www.ncbi.nlm.nih.gov/pubmed/24625050 http://dx.doi.org/10.1021/ja501782r

Ejemplares similares

Scalable, enantioselective taxane total synthesis
por: Mendoza, Abraham, et al.
Publicado: (2011)

11-Step Total Synthesis of Pallambins C and D
por: Martinez, Luisruben P., et al.
Publicado: (2016)

Applications of C–H Functionalization Logic to Cyclobutane Synthesis
por: Gutekunst, Will R., et al.
Publicado: (2014)

11-Step Total Synthesis of Araiosamines
por: Tian, Maoqun, et al.
Publicado: (2016)

11-Step Total Synthesis of (−)-Maoecrystal V
por: Cernijenko, Artiom, et al.
Publicado: (2016)

Scalable Synthesis of (−)-Thapsigargin
por: Chu, Hang, et al.
Publicado: (2016)

Guided Desaturation of Unactivated Aliphatics
por: Voica, Ana-Florina, et al.
Publicado: (2012)

Mechanistic Insights into Two-Phase Radical C–H Arylations
por: Baxter, Ryan D., et al.
Publicado: (2015)

Nineteen-Step Total Synthesis of (+)-Phorbol
por: Kawamura, Shuhei, et al.
Publicado: (2016)

A landmark in drug discovery based on complex natural product synthesis
por: Kawano, Satoshi, et al.
Publicado: (2019)

Antroquinonol A: Scalable Synthesis and Preclinical Biology of a Phase 2 Drug Candidate
por: Villaume, Matthew T., et al.
Publicado: (2015)

Synthesis of (+)-Cortistatin A
por: Shenvi, Ryan A., et al.
Publicado: (2008)

Total Synthesis of Dixiamycin B by Electrochemical Oxidation
por: Rosen, Brandon R., et al.
Publicado: (2014)

A Unified Approach to ent-Atisane Diterpenes and Related Alkaloids: Synthesis of (−)-Methyl Atisenoate, (−)-Isoatisine, and the Hetidine Skeleton
por: Cherney, Emily C., et al.
Publicado: (2014)

Convergent total synthesis of (+)-calcipotriol: A scalable, modular approach to vitamin D analogs
por: Gu, Jieyu, et al.
Publicado: (2022)

Molecular breeding of Saccharomyces cerevisiae with high RNA content by harnessing essential ribosomal RNA transcription regulator
por: Sasano, Yu, et al.
Publicado: (2017)

CRISPR-PCS: a powerful new approach to inducing multiple chromosome splitting in Saccharomyces cerevisiae
por: Sasano, Yu, et al.
Publicado: (2016)

Development of a Concise Synthesis of Ouabagenin and Hydroxylated Corticosteroid Analogues
por: Renata, Hans, et al.
Publicado: (2015)

Divergent Synthesis of Pyrone Diterpenes via Radical Cross Coupling
por: Merchant, Rohan R., et al.
Publicado: (2018)

Total Synthesis of Kibdelomycin
por: He, Chi, et al.
Publicado: (2022)

Axinellamines as Broad-Spectrum Antibacterial Agents: Scalable Synthesis and Biology
por: Rodriguez, Rodrigo A., et al.
Publicado: (2014)

Cellular mechanisms contributing to multiple stress tolerance in Saccharomyces cerevisiae strains with potential use in high-temperature ethanol fermentation
por: Kitichantaropas, Yasin, et al.
Publicado: (2016)

Synthesis and crystal structures of two new tin bis(carboranylamidinate) complexes
por: Harmgarth, Nicole, et al.
Publicado: (2017)

Precise Vapor-Phase Synthesis of Two-Dimensional Atomic Single Crystals
por: Zhao, Shasha, et al.
Publicado: (2019)

Modular Enantioselective Synthesis of cis-Cyclopropanes through Self-Sensitized Stereoselective Photodecarboxylation with Benzothiazolines
por: Costantini, Matteo, et al.
Publicado: (2021)

Possible Natural Hybridization of Two Morphologically Distinct Species of Acropora (Cnidaria, Scleractinia) in the Pacific: Fertilization and Larval Survival Rates
por: Isomura, Naoko, et al.
Publicado: (2013)

Chromosome XII context is important for rDNA function in yeast
por: Kim, Yeon-Hee, et al.
Publicado: (2006)

Genome-wide construction of a series of designed segmental aneuploids in Saccharomyces cerevisiae
por: Natesuntorn, Waranya, et al.
Publicado: (2015)

Modular Access to Diverse Chemiluminescent Dioxetane‐Luminophores through Convergent Synthesis
por: Gnaim, Samer, et al.
Publicado: (2022)

A Practical and Catalytic Reductive Olefin Coupling
por: Lo, Julian C., et al.
Publicado: (2014)

Genome-wide mapping of unexplored essential regions in the Saccharomyces cerevisiae genome: evidence for hidden synthetic lethal combinations in a genetic interaction network
por: Kaboli, Saeed, et al.
Publicado: (2014)

Academia–Industry Symbiosis in Organic Chemistry
por: Michaudel, Quentin, et al.
Publicado: (2015)

Scalable Synthesis of Piperazines Enabled by Visible-Light Irradiation and Aluminum Organometallics
por: Suárez-Pantiga, Samuel, et al.
Publicado: (2015)

Radicals: Reactive Intermediates with Translational Potential
por: Yan, Ming, et al.
Publicado: (2016)

Synthesis and properties of SiO(2)/SiO(2)@Ag two-phase STFs
por: He, Caiting, et al.
Publicado: (2023)

Modular Synthesis of (Borylmethyl)silanes through Orthogonal Functionalization of a Carbon Atom
por: Chowdhury, Rajdip, et al.
Publicado: (2023)

Scalable Access to Arylomycins via C–H Functionalization Logic
por: Peters, David S., et al.
Publicado: (2018)

Fabrication of Cell-Loaded Two-Phase 3D Constructs for Tissue Engineering
por: Zehnder, Tobias, et al.
Publicado: (2016)

Frequency synthesis by phase lock /
por: Egan, William F.
Publicado: (2000)

Solid-Phase Synthesis of s-Tetrazines
por: Alghamdi, Zainab S., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_hc7g2343p3qmgo4173d4e5qd2f