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Sequential “Click” – “Photo-Click” Cross-Linker for Catalyst-Free Ligation of Azide-Tagged Substrates

[Image: see text] Heterobifunctional linker allows for selective catalyst-free ligation of two different azide-tagged substrates via strained-promoted azide–alkyne cycloaddition (SPAAC). The linker contains an azadibenzocyclooctyne (ADIBO) moiety on one end and a cyclopropenone-masked dibenzocyclooc...

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Detalles Bibliográficos
Autores principales: Arumugam, Selvanathan, Popik, Vladimir V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985855/
https://www.ncbi.nlm.nih.gov/pubmed/24548078
http://dx.doi.org/10.1021/jo500143v