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Distinct Conformational Transition Patterns of Noncoding 7SK snRNA and HIV TAR RNAs upon Tat Binding

[Image: see text] Noncoding 7SK snRNA is believed to play an important role in the recruitment of P-TEFb by viral protein Tat to stimulate HIV processive transcription. Because HIV-2 TAR RNA and 7SK both evolved to feature a dinucleotide bulge region, compared to the trinucleotide bulge for HIV-1 TA...

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Detalles Bibliográficos
Autores principales:	Lu, Jia, Wong, Vivian, Zhang, Yi, Tran, Trung, Zhao, Liang, Xia, Amy, Xia, Tianbing, Qi, Xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985858/ https://www.ncbi.nlm.nih.gov/pubmed/24422492 http://dx.doi.org/10.1021/bi401131z

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