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Impact of Bilayer Lipid Composition on the Structure and Topology of the Transmembrane Amyloid Precursor C99 Protein
[Image: see text] C99 (also known as β-CTF) is the 99 residue transmembrane C-terminal domain (residues 672–770) of the amyloid precursor protein and is the immediate precursor of the amyloid-β (Aβ) polypeptides. To test the dependence of the C99 structure on the composition of the host model membra...
Autores principales: | Song, Yuanli, Mittendorf, Kathleen F., Lu, Zhenwei, Sanders, Charles R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985881/ https://www.ncbi.nlm.nih.gov/pubmed/24564538 http://dx.doi.org/10.1021/ja4114374 |
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