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Ligand-Controlled Asymmetric Arylation of Aliphatic α-Amino Anion Equivalents
[Image: see text] A palladium-catalyzed asymmetric arylation of 9-aminofluorene-derived imines using a chiral dialkylbiaryl phosphine as the supporting ligand has been developed. This transformation allows for enantioselective access to a diverse range of α-branched benzylamines.
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985922/ https://www.ncbi.nlm.nih.gov/pubmed/24621247 http://dx.doi.org/10.1021/ja501560x |
| _version_ | 1782311645560700928 |
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| author | Zhu, Ye Buchwald, Stephen L. |
| author_facet | Zhu, Ye Buchwald, Stephen L. |
| author_sort | Zhu, Ye |
| collection | PubMed |
| description | [Image: see text] A palladium-catalyzed asymmetric arylation of 9-aminofluorene-derived imines using a chiral dialkylbiaryl phosphine as the supporting ligand has been developed. This transformation allows for enantioselective access to a diverse range of α-branched benzylamines. |
| format | Online Article Text |
| id | pubmed-3985922 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2014 |
| publisher | American Chemical
Society |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-39859222015-03-12 Ligand-Controlled Asymmetric Arylation of Aliphatic α-Amino Anion Equivalents Zhu, Ye Buchwald, Stephen L. J Am Chem Soc [Image: see text] A palladium-catalyzed asymmetric arylation of 9-aminofluorene-derived imines using a chiral dialkylbiaryl phosphine as the supporting ligand has been developed. This transformation allows for enantioselective access to a diverse range of α-branched benzylamines. American Chemical Society 2014-03-12 2014-03-26 /pmc/articles/PMC3985922/ /pubmed/24621247 http://dx.doi.org/10.1021/ja501560x Text en Copyright © 2014 American Chemical Society |
| spellingShingle | Zhu, Ye Buchwald, Stephen L. Ligand-Controlled Asymmetric Arylation of Aliphatic α-Amino Anion Equivalents |
| title | Ligand-Controlled Asymmetric Arylation of Aliphatic α-Amino Anion Equivalents |
| title_full | Ligand-Controlled Asymmetric Arylation of Aliphatic α-Amino Anion Equivalents |
| title_fullStr | Ligand-Controlled Asymmetric Arylation of Aliphatic α-Amino Anion Equivalents |
| title_full_unstemmed | Ligand-Controlled Asymmetric Arylation of Aliphatic α-Amino Anion Equivalents |
| title_short | Ligand-Controlled Asymmetric Arylation of Aliphatic α-Amino Anion Equivalents |
| title_sort | ligand-controlled asymmetric arylation of aliphatic α-amino anion equivalents |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985922/ https://www.ncbi.nlm.nih.gov/pubmed/24621247 http://dx.doi.org/10.1021/ja501560x |
| work_keys_str_mv | AT zhuye ligandcontrolledasymmetricarylationofaliphaticaaminoanionequivalents AT buchwaldstephenl ligandcontrolledasymmetricarylationofaliphaticaaminoanionequivalents |