Development of a Suzuki Cross-Coupling Reaction between 2-Azidoarylboronic Pinacolate Esters and Vinyl Triflates To Enable the Synthesis of [2,3]-Fused Indole Heterocycles

[Image: see text] The scope and limitations of a Suzuki reaction between 2-azidoarylboronic acid pinacolate esters and vinyl triflates are reported. This cross-coupling reaction enables the regioselective synthesis of indoles after a subsequent Rh(II)(2)-catalyzed sp(2)-C–H bond amination reaction....

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Detalles Bibliográficos
Autores principales: Jana, Navendu, Nguyen, Quyen, Driver, Tom G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985933/
https://www.ncbi.nlm.nih.gov/pubmed/24571492
http://dx.doi.org/10.1021/jo500252e
Descripción
Sumario:[Image: see text] The scope and limitations of a Suzuki reaction between 2-azidoarylboronic acid pinacolate esters and vinyl triflates are reported. This cross-coupling reaction enables the regioselective synthesis of indoles after a subsequent Rh(II)(2)-catalyzed sp(2)-C–H bond amination reaction.

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