Strength of Axial Water Ligation in Substrate-Free Cytochrome P450s Is Isoform Dependent

[Image: see text] The heme-containing cytochrome P450s exhibit isoform-dependent ferric spin equilibria in the resting state and differential substrate-dependent spin equilibria. The basis for these differences is not well understood. Here, magnetic circular dichroism (MCD) reveals significant diffe...

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Detalles Bibliográficos
Autores principales: Conner, Kip P., Schimpf, Alina M., Cruce, Alex A., McLean, Kirsty J., Munro, Andrew W., Frank, Daniel J., Krzyaniak, Matthew D., Ortiz de Montellano, Paul, Bowman, Michael K., Atkins, William M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985942/
https://www.ncbi.nlm.nih.gov/pubmed/24576089
http://dx.doi.org/10.1021/bi401547j

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