High-Resolution Structures and Orientations of Antimicrobial Peptides Piscidin 1 and Piscidin 3 in Fluid Bilayers Reveal Tilting, Kinking, and Bilayer Immersion

[Image: see text] While antimicrobial peptides (AMPs) have been widely investigated as potential therapeutics, high-resolution structures obtained under biologically relevant conditions are lacking. Here, the high-resolution structures of the homologous 22-residue long AMPs piscidin 1 (p1) and pisci...

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Detalles Bibliográficos
Autores principales: Perrin, B. Scott, Tian, Ye, Fu, Riqiang, Grant, Christopher V., Chekmenev, Eduard Y., Wieczorek, William E., Dao, Alexander E., Hayden, Robert M., Burzynski, Caitlin M., Venable, Richard M., Sharma, Mukesh, Opella, Stanley J., Pastor, Richard W., Cotten, Myriam L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985945/
https://www.ncbi.nlm.nih.gov/pubmed/24410116
http://dx.doi.org/10.1021/ja411119m

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