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Structure of Human PIR1, an Atypical Dual-Specificity Phosphatase

[Image: see text] PIR1 is an atypical dual-specificity phosphatase (DSP) that dephosphorylates RNA with a higher specificity than phosphoproteins. Here we report the atomic structure of a catalytically inactive mutant (C152S) of the human PIR1 phosphatase core (PIR1-core, residues 29–205), refined a...

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Detalles Bibliográficos
Autores principales:	Sankhala, Rajeshwer Singh, Lokareddy, Ravi Kumar, Cingolani, Gino
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985963/ https://www.ncbi.nlm.nih.gov/pubmed/24447265 http://dx.doi.org/10.1021/bi401240x

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