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Strictly Conserved Lysine of Prolyl-tRNA Synthetase Editing Domain Facilitates Binding and Positioning of Misacylated tRNA(Pro)

[Image: see text] To ensure high fidelity in translation, many aminoacyl-tRNA synthetases, enzymes responsible for attaching specific amino acids to cognate tRNAs, require proof-reading mechanisms. Most bacterial prolyl-tRNA synthetases (ProRSs) misactivate alanine and employ a post-transfer editing...

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Detalles Bibliográficos
Autores principales:	Bartholow, Thomas G., Sanford, Brianne L., Cao, Bach, Schmit, Heidi L., Johnson, James M., Meitzner, Jet, Bhattacharyya, Sudeep, Musier-Forsyth, Karin, Hati, Sanchita
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986007/ https://www.ncbi.nlm.nih.gov/pubmed/24450765 http://dx.doi.org/10.1021/bi401279r

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