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Regional-Specific Effects of Ovarian Hormone Loss on Synaptic Plasticity in Adult Human APOE Targeted Replacement Mice

The human apolipoprotein ε4 allele (APOE4) has been implicated as one of the strongest genetic risk factors associated with Alzheimer’s disease (AD) and in influencing normal cognitive functioning. Previous studies have demonstrated that mice expressing human apoE4 display deficits in behavioral and...

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Detalles Bibliográficos
Autores principales:	Klein, Rebecca C., Saini, Shyla, Risher, M-Louise, Acheson, Shawn K., Fleming, Rebekah L., Sexton, Hannah G., Swartzwelder, H. Scott, Moore, Scott D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986067/ https://www.ncbi.nlm.nih.gov/pubmed/24732142 http://dx.doi.org/10.1371/journal.pone.0094071

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