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Evolution of Proliferation and the Angiogenic Switch in Tumors with High Clonal Diversity
Natural selection among tumor cell clones is thought to produce hallmark properties of malignancy. Efforts to understand evolution of one such hallmark—the angiogenic switch—has suggested that selection for angiogenesis can “run away” and generate a hypertumor, a form of evolutionary suicide by extr...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986075/ https://www.ncbi.nlm.nih.gov/pubmed/24732428 http://dx.doi.org/10.1371/journal.pone.0091992 |