Mycobactericidal Activity of Sutezolid (PNU-100480) in Sputum (EBA) and Blood (WBA) of Patients with Pulmonary Tuberculosis

RATIONALE: Sutezolid (PNU-100480) is a linezolid analog with superior bactericidal activity against Mycobacterium tuberculosis in the hollow fiber, whole blood and mouse models. Like linezolid, it is unaffected by mutations conferring resistance to standard TB drugs. This study of sutezolid is its f...

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Detalles Bibliográficos
Autores principales: Wallis, Robert S., Dawson, Rodney, Friedrich, Sven O., Venter, Amour, Paige, Darcy, Zhu, Tong, Silvia, Annette, Gobey, Jason, Ellery, Craig, Zhang, Yao, Eisenach, Kathleen, Miller, Paul, Diacon, Andreas H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986205/
https://www.ncbi.nlm.nih.gov/pubmed/24732289
http://dx.doi.org/10.1371/journal.pone.0094462

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986205/
https://www.ncbi.nlm.nih.gov/pubmed/24732289
http://dx.doi.org/10.1371/journal.pone.0094462

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