Targeted BRAF Inhibition Impacts Survival in Melanoma Patients with High Levels of Wnt/β-Catenin Signaling

Unprecedented clinical responses have been reported in advanced stage metastatic melanoma patients treated with targeted inhibitors of constitutively activated mutant BRAF, which is present in approximately half of all melanomas. We and others have previously observed an association of elevated nucl...

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Detalles Bibliográficos
Autores principales: Chien, Andy J., Haydu, Lauren E., Biechele, Travis L., Kulikauskas, Rima M., Rizos, Helen, Kefford, Richard F., Scolyer, Richard A., Moon, Randall T., Long, Georgina V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986217/
https://www.ncbi.nlm.nih.gov/pubmed/24733413
http://dx.doi.org/10.1371/journal.pone.0094748

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986217/
https://www.ncbi.nlm.nih.gov/pubmed/24733413
http://dx.doi.org/10.1371/journal.pone.0094748

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