Characterization of a fusion protein of RGD4C and the β-lactamase variant for antibody-directed enzyme prodrug therapy

Antibody-directed enzyme prodrug therapy (ADEPT) delivers chemotherapeutic agents in high concentration to tumor tissue, while minimizing systemic drug exposure. ADEPT has been reported to be an attractive approach for improving the efficacy of cancer therapy. A previously reported β-lactamase was f...

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Detalles Bibliográficos
Autores principales: Zhou, Xiaoliang, Wang, Hao, Shi, Peiji, Meng, Ai-min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986274/
https://www.ncbi.nlm.nih.gov/pubmed/24748803
http://dx.doi.org/10.2147/OTT.S59346

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986274/
https://www.ncbi.nlm.nih.gov/pubmed/24748803
http://dx.doi.org/10.2147/OTT.S59346

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