A randomized, double-blind, placebo-controlled, dose-ranging study using Genz-644470 and sevelamer carbonate in hyperphosphatemic chronic kidney disease patients on hemodialysis

BACKGROUND: Genz-644470 is a new, nonabsorbed phosphate binding polymer. In an in vitro competitive phosphate binding assay, Genz-644470 bound significantly more phosphate per gram than sevelamer. As a consequence, this clinical study evaluated the ability of Genz-644470 to lower serum phosphorus in...

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Detalles Bibliográficos
Autores principales: Moustafa, Moustafa, Lehrner, Lawrence, Al-Saghir, Fahd, Smith, Mark, Goyal, Sunita, Dillon, Maureen, Hunter, John, Holmes-Farley, Randy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986335/
https://www.ncbi.nlm.nih.gov/pubmed/24748812
http://dx.doi.org/10.2147/IJNRD.S56217

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