Zinc Regulates the Acute Phase Response and Serum Amyloid A Production in Response to Sepsis through JAK-STAT3 Signaling

Sepsis rapidly activates the host inflammatory response and acute phase response. Severe sepsis, complicated by multiple organ failure, is associated with overwhelming inflammation and high mortality. We previously observed that zinc (Zn) deficiency significantly increases mortality in a mouse model...

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Detalles Bibliográficos
Autores principales: Liu, Ming-Jie, Bao, Shengying, Napolitano, Jessica R., Burris, Dara L., Yu, Lianbo, Tridandapani, Susheela, Knoell, Daren L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986341/
https://www.ncbi.nlm.nih.gov/pubmed/24732911
http://dx.doi.org/10.1371/journal.pone.0094934

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