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Unaltered Striatal Dopamine Release Levels in Young Parkin Knockout, Pink1 Knockout, DJ-1 Knockout and LRRK2 R1441G Transgenic Mice
Parkinson's disease (PD) is one of the most prevalent neurodegenerative brain diseases; it is accompanied by extensive loss of dopamine (DA) neurons of the substantia nigra that project to the putamen, leading to impaired motor functions. Several genes have been associated with hereditary forms...
Autores principales: | Sanchez, Gonzalo, Varaschin, Rafael K., Büeler, Hansruedi, Marcogliese, Paul C., Park, David S., Trudeau, Louis-Eric |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986353/ https://www.ncbi.nlm.nih.gov/pubmed/24733019 http://dx.doi.org/10.1371/journal.pone.0094826 |
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