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An Agomir of miR-144-3p Accelerates Plaque Formation through Impairing Reverse Cholesterol Transport and Promoting Pro-Inflammatory Cytokine Production

AIMS: ATP-binding cassette transporter A1 (ABCA1) mediates the efflux of cholesterol and phospholipids to lipid-poor apolipoproteins, which then form nascent HDL, a key step in the mechanism of reverse cholesterol transport (RCT). While a series of microRNAs (miRNAs) have been identified as potent p...

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Detalles Bibliográficos
Autores principales: Hu, Yan-Wei, Hu, Ya-Rong, Zhao, Jia-Yi, Li, Shu-Fen, Ma, Xin, Wu, Shao-Guo, Lu, Jing-Bo, Qiu, Yu-Rong, Sha, Yan-Hua, Wang, Yan-Chao, Gao, Ji-Juan, Zheng, Lei, Wang, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986368/
https://www.ncbi.nlm.nih.gov/pubmed/24733347
http://dx.doi.org/10.1371/journal.pone.0094997