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An Agomir of miR-144-3p Accelerates Plaque Formation through Impairing Reverse Cholesterol Transport and Promoting Pro-Inflammatory Cytokine Production
AIMS: ATP-binding cassette transporter A1 (ABCA1) mediates the efflux of cholesterol and phospholipids to lipid-poor apolipoproteins, which then form nascent HDL, a key step in the mechanism of reverse cholesterol transport (RCT). While a series of microRNAs (miRNAs) have been identified as potent p...
Autores principales: | Hu, Yan-Wei, Hu, Ya-Rong, Zhao, Jia-Yi, Li, Shu-Fen, Ma, Xin, Wu, Shao-Guo, Lu, Jing-Bo, Qiu, Yu-Rong, Sha, Yan-Hua, Wang, Yan-Chao, Gao, Ji-Juan, Zheng, Lei, Wang, Qian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986368/ https://www.ncbi.nlm.nih.gov/pubmed/24733347 http://dx.doi.org/10.1371/journal.pone.0094997 |
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