Glucagon Stimulates Hepatic FGF21 Secretion through a PKA- and EPAC-Dependent Posttranscriptional Mechanism

Previous studies have shown that whole body deletion of the glucagon receptor suppresses the ability of starvation to increase hepatic fibroblast growth factor 21 (FGF21) expression and plasma FGF21 concentration. Here, we investigate the mechanism by which glucagon receptor activation increases hep...

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Detalles Bibliográficos
Autores principales: Cyphert, Holly A., Alonge, Kimberly M., Ippagunta, Siri M., Hillgartner, F. Bradley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986400/
https://www.ncbi.nlm.nih.gov/pubmed/24733293
http://dx.doi.org/10.1371/journal.pone.0094996

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986400/
https://www.ncbi.nlm.nih.gov/pubmed/24733293
http://dx.doi.org/10.1371/journal.pone.0094996

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