Huntingtin Regulates Mammary Stem Cell Division and Differentiation

Little is known about the mechanisms of mitotic spindle orientation during mammary gland morphogenesis. Here, we report the presence of huntingtin, the protein mutated in Huntington’s disease, in mouse mammary basal and luminal cells throughout mammogenesis. Keratin 5-driven depletion of huntingtin...

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Detalles Bibliográficos
Autores principales: Elias, Salah, Thion, Morgane S., Yu, Hua, Sousa, Cristovao Marques, Lasgi, Charlène, Morin, Xavier, Humbert, Sandrine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986500/
https://www.ncbi.nlm.nih.gov/pubmed/24749073
http://dx.doi.org/10.1016/j.stemcr.2014.02.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986500/
https://www.ncbi.nlm.nih.gov/pubmed/24749073
http://dx.doi.org/10.1016/j.stemcr.2014.02.011

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