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Huntingtin Regulates Mammary Stem Cell Division and Differentiation
Little is known about the mechanisms of mitotic spindle orientation during mammary gland morphogenesis. Here, we report the presence of huntingtin, the protein mutated in Huntington’s disease, in mouse mammary basal and luminal cells throughout mammogenesis. Keratin 5-driven depletion of huntingtin...
Autores principales: | Elias, Salah, Thion, Morgane S., Yu, Hua, Sousa, Cristovao Marques, Lasgi, Charlène, Morin, Xavier, Humbert, Sandrine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986500/ https://www.ncbi.nlm.nih.gov/pubmed/24749073 http://dx.doi.org/10.1016/j.stemcr.2014.02.011 |
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