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FOXO3 Promotes Quiescence in Adult Muscle Stem Cells during the Process of Self-Renewal

Skeletal muscle stem cells, or “satellite cells” (SCs), are required for the regeneration of damaged muscle tissue. Although SCs self-renew during regeneration, the mechanisms that govern SC re-entry into quiescence remain elusive. We show that FOXO3, a member of the forkhead family of transcription...

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Detalles Bibliográficos
Autores principales: Gopinath, Suchitra D., Webb, Ashley E., Brunet, Anne, Rando, Thomas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986584/
https://www.ncbi.nlm.nih.gov/pubmed/24749067
http://dx.doi.org/10.1016/j.stemcr.2014.02.002