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Downregulation of IRS-1 in adipose tissue of offspring of obese mice is programmed cell-autonomously through post-transcriptional mechanisms()

We determined the effects of maternal diet-induced obesity on offspring adipose tissue insulin signalling and miRNA expression in the aetiology of insulin resistance in later life. Although body composition and glucose tolerance of 8-week-old male offspring of obese dams were not dysregulated, serum...

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Detalles Bibliográficos
Autores principales:	Fernandez-Twinn, Denise S., Alfaradhi, Maria Z., Martin-Gronert, Malgorzata S., Duque-Guimaraes, Daniella E., Piekarz, Ana, Ferland-McCollough, David, Bushell, Martin, Ozanne, Susan E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986586/ https://www.ncbi.nlm.nih.gov/pubmed/24749062 http://dx.doi.org/10.1016/j.molmet.2014.01.007

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