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The impact of frontal and cerebellar lesions on decision making: evidence from the Iowa Gambling Task
Although the frontal lobes have traditionally been considered the neural substrates of executive functioning (EF), recent studies have suggested that other structures, such as the cerebellum, may be associated with these abilities. The role of the cerebellum has only been sparsely investigated in co...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986592/ https://www.ncbi.nlm.nih.gov/pubmed/24782697 http://dx.doi.org/10.3389/fnins.2014.00061 |
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author | Cardoso, Caroline de Oliveira Branco, Laura Damiani Cotrena, Charles Kristensen, Christian Haag Schneider Bakos, Daniela Di Giorge Fonseca, Rochele Paz |
author_facet | Cardoso, Caroline de Oliveira Branco, Laura Damiani Cotrena, Charles Kristensen, Christian Haag Schneider Bakos, Daniela Di Giorge Fonseca, Rochele Paz |
author_sort | Cardoso, Caroline de Oliveira |
collection | PubMed |
description | Although the frontal lobes have traditionally been considered the neural substrates of executive functioning (EF), recent studies have suggested that other structures, such as the cerebellum, may be associated with these abilities. The role of the cerebellum has only been sparsely investigated in connection with decision making (DM), an important component of EF, and the few results obtained on this front have been inconclusive. The current study sought to investigate the role of the cerebellum in DM by comparing the performance of patients with cerebellar strokes, frontal-damaged patients, and a healthy control group on the Iowa Gambling Task (IGT). A total of nine cerebellar-damaged adults participated in the study, as well as nine individuals with frontal strokes and 18 control individuals. Patients were administered a version of the IGT adapted to the population of Southern Brazil. There was a marginal difference in mean IGT net scores between the two clinical groups, although both displayed impaired performance as compared to the control group. Overall, the DM ability of patients with cerebellar damage proved to be more preserved than that of individuals with frontal lobe strokes, but less preserved than that of the control group. These data suggested that, while the frontal lobes may be the most important brain structures for DM, the cerebellum might also play an active role in this cognitive function. Future studies assessing participants with lesions in different cerebellar regions and hemispheres will prove invaluable for the understanding of the neural structures involved in DM, and make significant contributions to the globalist-localizationist debate in DM neuroscience. |
format | Online Article Text |
id | pubmed-3986592 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-39865922014-04-29 The impact of frontal and cerebellar lesions on decision making: evidence from the Iowa Gambling Task Cardoso, Caroline de Oliveira Branco, Laura Damiani Cotrena, Charles Kristensen, Christian Haag Schneider Bakos, Daniela Di Giorge Fonseca, Rochele Paz Front Neurosci Neuroscience Although the frontal lobes have traditionally been considered the neural substrates of executive functioning (EF), recent studies have suggested that other structures, such as the cerebellum, may be associated with these abilities. The role of the cerebellum has only been sparsely investigated in connection with decision making (DM), an important component of EF, and the few results obtained on this front have been inconclusive. The current study sought to investigate the role of the cerebellum in DM by comparing the performance of patients with cerebellar strokes, frontal-damaged patients, and a healthy control group on the Iowa Gambling Task (IGT). A total of nine cerebellar-damaged adults participated in the study, as well as nine individuals with frontal strokes and 18 control individuals. Patients were administered a version of the IGT adapted to the population of Southern Brazil. There was a marginal difference in mean IGT net scores between the two clinical groups, although both displayed impaired performance as compared to the control group. Overall, the DM ability of patients with cerebellar damage proved to be more preserved than that of individuals with frontal lobe strokes, but less preserved than that of the control group. These data suggested that, while the frontal lobes may be the most important brain structures for DM, the cerebellum might also play an active role in this cognitive function. Future studies assessing participants with lesions in different cerebellar regions and hemispheres will prove invaluable for the understanding of the neural structures involved in DM, and make significant contributions to the globalist-localizationist debate in DM neuroscience. Frontiers Media S.A. 2014-04-08 /pmc/articles/PMC3986592/ /pubmed/24782697 http://dx.doi.org/10.3389/fnins.2014.00061 Text en Copyright © 2014 Cardoso, Branco, Cotrena, Kristensen, Schneider Bakos and Fonseca. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Neuroscience Cardoso, Caroline de Oliveira Branco, Laura Damiani Cotrena, Charles Kristensen, Christian Haag Schneider Bakos, Daniela Di Giorge Fonseca, Rochele Paz The impact of frontal and cerebellar lesions on decision making: evidence from the Iowa Gambling Task |
title | The impact of frontal and cerebellar lesions on decision making: evidence from the Iowa Gambling Task |
title_full | The impact of frontal and cerebellar lesions on decision making: evidence from the Iowa Gambling Task |
title_fullStr | The impact of frontal and cerebellar lesions on decision making: evidence from the Iowa Gambling Task |
title_full_unstemmed | The impact of frontal and cerebellar lesions on decision making: evidence from the Iowa Gambling Task |
title_short | The impact of frontal and cerebellar lesions on decision making: evidence from the Iowa Gambling Task |
title_sort | impact of frontal and cerebellar lesions on decision making: evidence from the iowa gambling task |
topic | Neuroscience |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986592/ https://www.ncbi.nlm.nih.gov/pubmed/24782697 http://dx.doi.org/10.3389/fnins.2014.00061 |
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