CRIPTO/GRP78 Signaling Maintains Fetal and Adult Mammary Stem Cells Ex Vivo

Little is known about the extracellular signaling factors that govern mammary stem cell behavior. Here, we identify CRIPTO and its cell-surface receptor GRP78 as regulators of stem cell behavior in isolated fetal and adult mammary epithelial cells. We develop a CRIPTO antagonist that promotes differ...

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Detalles Bibliográficos
Autores principales: Spike, Benjamin T., Kelber, Jonathan A., Booker, Evan, Kalathur, Madhuri, Rodewald, Rose, Lipianskaya, Julia, La, Justin, He, Marielle, Wright, Tracy, Klemke, Richard, Wahl, Geoffrey M., Gray, Peter C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986630/
https://www.ncbi.nlm.nih.gov/pubmed/24749068
http://dx.doi.org/10.1016/j.stemcr.2014.02.010

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