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Comparison of somatic mutation calling methods in amplicon and whole exome sequence data
BACKGROUND: High-throughput sequencing is rapidly becoming common practice in clinical diagnosis and cancer research. Many algorithms have been developed for somatic single nucleotide variant (SNV) detection in matched tumor-normal DNA sequencing. Although numerous studies have compared the performa...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986649/ https://www.ncbi.nlm.nih.gov/pubmed/24678773 http://dx.doi.org/10.1186/1471-2164-15-244 |