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Structural models of the membrane anchors of envelope glycoproteins E1 and E2 from pestiviruses

The membrane anchors of viral envelope proteins play essential roles in cell entry. Recent crystal structures of the ectodomain of envelope protein E2 from a pestivirus suggest that E2 belongs to a novel structural class of membrane fusion machinery. Based on geometric constraints from the E2 struct...

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Detalles Bibliográficos
Autores principales: Wang, Jimin, Li, Yue, Modis, Yorgo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986810/
https://www.ncbi.nlm.nih.gov/pubmed/24725935
http://dx.doi.org/10.1016/j.virol.2014.02.015