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Successful Treatment with Propranolol in a Patient with a Segmental Hemangioma: A Case Report

The treatment of hemangiomas in infancy may be associated with significant morbidity. In addition to morbidity, an objective response cannot be obtained because of the absence of targeted therapeutic options. Herein, we present an infant with a segmental hemangioma and marked glucocorticoid toxicity...

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Detalles Bibliográficos
Autores principales: Küpeli, Serhan, Çimen, Derya, Küpeli, Begül Yağcı
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986956/
https://www.ncbi.nlm.nih.gov/pubmed/24744649
http://dx.doi.org/10.5505/tjh.2012.37233
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author Küpeli, Serhan
Çimen, Derya
Küpeli, Begül Yağcı
author_facet Küpeli, Serhan
Çimen, Derya
Küpeli, Begül Yağcı
author_sort Küpeli, Serhan
collection PubMed
description The treatment of hemangiomas in infancy may be associated with significant morbidity. In addition to morbidity, an objective response cannot be obtained because of the absence of targeted therapeutic options. Herein, we present an infant with a segmental hemangioma and marked glucocorticoid toxicity due to prior steroid therapy that was successfully treated with propranolol. Propranolol was tolerated well and no side effects were observed during the treatment. The only problem to occur was disease recurrence following the withdrawal of propranolol at age 13 months, which was not within the age of spontaneous regression (generally considered as >18 months).
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spelling pubmed-39869562014-04-17 Successful Treatment with Propranolol in a Patient with a Segmental Hemangioma: A Case Report Küpeli, Serhan Çimen, Derya Küpeli, Begül Yağcı Turk J Haematol Case Report The treatment of hemangiomas in infancy may be associated with significant morbidity. In addition to morbidity, an objective response cannot be obtained because of the absence of targeted therapeutic options. Herein, we present an infant with a segmental hemangioma and marked glucocorticoid toxicity due to prior steroid therapy that was successfully treated with propranolol. Propranolol was tolerated well and no side effects were observed during the treatment. The only problem to occur was disease recurrence following the withdrawal of propranolol at age 13 months, which was not within the age of spontaneous regression (generally considered as >18 months). Galenos Publishing 2012-06 2012-06-15 /pmc/articles/PMC3986956/ /pubmed/24744649 http://dx.doi.org/10.5505/tjh.2012.37233 Text en © Turkish Journal of Hematology, Published by Galenos Publishing. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Küpeli, Serhan
Çimen, Derya
Küpeli, Begül Yağcı
Successful Treatment with Propranolol in a Patient with a Segmental Hemangioma: A Case Report
title Successful Treatment with Propranolol in a Patient with a Segmental Hemangioma: A Case Report
title_full Successful Treatment with Propranolol in a Patient with a Segmental Hemangioma: A Case Report
title_fullStr Successful Treatment with Propranolol in a Patient with a Segmental Hemangioma: A Case Report
title_full_unstemmed Successful Treatment with Propranolol in a Patient with a Segmental Hemangioma: A Case Report
title_short Successful Treatment with Propranolol in a Patient with a Segmental Hemangioma: A Case Report
title_sort successful treatment with propranolol in a patient with a segmental hemangioma: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986956/
https://www.ncbi.nlm.nih.gov/pubmed/24744649
http://dx.doi.org/10.5505/tjh.2012.37233
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