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Ruscogenin ameliorates diabetic nephropathy by its anti-inflammatory and anti-fibrotic effects in streptozotocin-induced diabetic rat
BACKGROUND: Ruscogenin is a major steroid sapogenin in the traditional Chinese herb Ophiopogon japonicus that have multiple bioactivities. Recent studies have demonstrated that ruscogenin is involved in down-regulation of intercellular adhesion molecule-1 (ICAM-1) and nuclear factor-κB (NF-κB) activ...
Autores principales: | Lu, Hung-Jen, Tzeng, Thing-Fong, Liou, Shorong-Shii, Da Lin, Sheng, Wu, Ming-Chang, Liu, I-Min |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986976/ https://www.ncbi.nlm.nih.gov/pubmed/24666993 http://dx.doi.org/10.1186/1472-6882-14-110 |
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