Association study of newly identified age-related macular degeneration susceptible loci SOD2, MBP, and C8orf42 in Han Chinese population

A recent genome-wide association study has reported three newly identified susceptible loci (rs2842992 near the gene SOD2, rs1789110 near the gene MBP and rs722782 near the gene C8orf42) to be associated with the geographic atrophy subtype of age-related macular degeneration in European-descent popu...

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Autores principales: Kan, Mengyuan, Liu, Fatao, Weng, Xiaoling, Ye, Junyi, Wang, Ting, Xu, Mingqing, He, Lin, Liu, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986977/
https://www.ncbi.nlm.nih.gov/pubmed/24667176
http://dx.doi.org/10.1186/1746-1596-9-73
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author Kan, Mengyuan
Liu, Fatao
Weng, Xiaoling
Ye, Junyi
Wang, Ting
Xu, Mingqing
He, Lin
Liu, Yun
author_facet Kan, Mengyuan
Liu, Fatao
Weng, Xiaoling
Ye, Junyi
Wang, Ting
Xu, Mingqing
He, Lin
Liu, Yun
author_sort Kan, Mengyuan
collection PubMed
description A recent genome-wide association study has reported three newly identified susceptible loci (rs2842992 near the gene SOD2, rs1789110 near the gene MBP and rs722782 near the gene C8orf42) to be associated with the geographic atrophy subtype of age-related macular degeneration in European-descent population. We investigated the correlation between these variants and advanced age-related macular degeneration for the first time in a Han Chinese cohort; however, no evidence supports these previously identified loci contribute to advanced age-related macular degeneration susceptibility in Chinese population.
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spelling pubmed-39869772014-04-16 Association study of newly identified age-related macular degeneration susceptible loci SOD2, MBP, and C8orf42 in Han Chinese population Kan, Mengyuan Liu, Fatao Weng, Xiaoling Ye, Junyi Wang, Ting Xu, Mingqing He, Lin Liu, Yun Diagn Pathol Letter to the Editor A recent genome-wide association study has reported three newly identified susceptible loci (rs2842992 near the gene SOD2, rs1789110 near the gene MBP and rs722782 near the gene C8orf42) to be associated with the geographic atrophy subtype of age-related macular degeneration in European-descent population. We investigated the correlation between these variants and advanced age-related macular degeneration for the first time in a Han Chinese cohort; however, no evidence supports these previously identified loci contribute to advanced age-related macular degeneration susceptibility in Chinese population. BioMed Central 2014-03-25 /pmc/articles/PMC3986977/ /pubmed/24667176 http://dx.doi.org/10.1186/1746-1596-9-73 Text en Copyright © 2014 Kan et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Letter to the Editor
Kan, Mengyuan
Liu, Fatao
Weng, Xiaoling
Ye, Junyi
Wang, Ting
Xu, Mingqing
He, Lin
Liu, Yun
Association study of newly identified age-related macular degeneration susceptible loci SOD2, MBP, and C8orf42 in Han Chinese population
title Association study of newly identified age-related macular degeneration susceptible loci SOD2, MBP, and C8orf42 in Han Chinese population
title_full Association study of newly identified age-related macular degeneration susceptible loci SOD2, MBP, and C8orf42 in Han Chinese population
title_fullStr Association study of newly identified age-related macular degeneration susceptible loci SOD2, MBP, and C8orf42 in Han Chinese population
title_full_unstemmed Association study of newly identified age-related macular degeneration susceptible loci SOD2, MBP, and C8orf42 in Han Chinese population
title_short Association study of newly identified age-related macular degeneration susceptible loci SOD2, MBP, and C8orf42 in Han Chinese population
title_sort association study of newly identified age-related macular degeneration susceptible loci sod2, mbp, and c8orf42 in han chinese population
topic Letter to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986977/
https://www.ncbi.nlm.nih.gov/pubmed/24667176
http://dx.doi.org/10.1186/1746-1596-9-73
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