Galectin-3 disruption impaired tumoral angiogenesis by reducing VEGF secretion from TGFβ1-induced macrophages

In order to study the role of galectin-3 in tumor angiogenesis associated with tumor-associated macrophages (TAM) and tumor parenchyma, the galectin-3 expression was reconstituted in Tm1 melanoma cell line that lacks this protein. Galectin-3-expressing cells (Tm1G3) and mock-vector transfected cells...

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Detalles Bibliográficos
Autores principales: Machado, Camila Maria Longo, Andrade, Luciana Nogueira Sousa, Teixeira, Verônica Rodrigues, Costa, Fabrício Falconi, Melo, Camila Morais, dos Santos, Sofia Nascimento, Nonogaki, Suely, Liu, Fu-Tong, Bernardes, Emerson Soares, Camargo, Anamaria Aranha, Chammas, Roger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Ltd 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3987071/
https://www.ncbi.nlm.nih.gov/pubmed/24421272
http://dx.doi.org/10.1002/cam4.173

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