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The effects of nonspecific HIF1α inhibitors on development of castrate resistance and metastases in prostate cancer

Expression of hypoxia-inducible factor (HIF)1α increases the risk of castrate-resistant prostate cancer (CRPC) and metastases in patients on androgen deprivation therapy (ADT) for prostate cancer (PC). We aimed to investigate the effects of nonspecific HIF1α inhibitors (Digoxin, metformin, and angio...

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Detalles Bibliográficos
Autores principales:	Ranasinghe, Weranja K B, Sengupta, Shomik, Williams, Scott, Chang, Mike, Shulkes, Arthur, Bolton, Damien M, Baldwin, Graham, Patel, Oneel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons Ltd 2014
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3987074/ https://www.ncbi.nlm.nih.gov/pubmed/24464861 http://dx.doi.org/10.1002/cam4.189

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