Effect of simvastatin on castration-resistant prostate cancer cells

BACKGROUND: In castration-resistant prostate cancer (CRPC), recent evidence has demonstrated the persistence of the intratumoral androgens. The multi-step androgen synthesis pathway originates from cholesterol, which can be obtained by cells from several major sources including intracellular synthes...

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Detalles Bibliográficos
Autores principales: Kim, Jenny Hanbi, Cox, Michael E, Wasan, Kishor M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3987159/
https://www.ncbi.nlm.nih.gov/pubmed/24666612
http://dx.doi.org/10.1186/1476-511X-13-56

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