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Comparative evaluation of sonographic ovarian morphology of Indian women with polycystic ovary syndrome versus those of normal women
OBJECTIVES: To study ovarian morphology by ultrasound in women with or without polycystic ovary syndrome (PCOS) and to establish cut-off values of these parameters in Indian women with PCOS. MATERIALS AND METHODS: A total of 119 consecutive women diagnosed PCOS and 77 apparently healthy women were e...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3987267/ https://www.ncbi.nlm.nih.gov/pubmed/24741513 http://dx.doi.org/10.4103/2230-8210.129108 |
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author | Ahmed, Sanjeed Pahwa, Shivani Das, Chandan Jyoti Mir, Farooq A Nisar, Sobia Jehangir, Majid Parveen, Shameem Rashid, Aafia Ganie, Mohd Ashraf |
author_facet | Ahmed, Sanjeed Pahwa, Shivani Das, Chandan Jyoti Mir, Farooq A Nisar, Sobia Jehangir, Majid Parveen, Shameem Rashid, Aafia Ganie, Mohd Ashraf |
author_sort | Ahmed, Sanjeed |
collection | PubMed |
description | OBJECTIVES: To study ovarian morphology by ultrasound in women with or without polycystic ovary syndrome (PCOS) and to establish cut-off values of these parameters in Indian women with PCOS. MATERIALS AND METHODS: A total of 119 consecutive women diagnosed PCOS and 77 apparently healthy women were enrolled. Transabdominal ultrasound examination was carried out to assess ovarian volume, stromal echogenecity, follicle number and size. Cut-off values of the above ovarian parameters with sensitivity, specificity, positive predictive value (PPV) and negative predictive values (NPV) were calculated. RESULTS: Sensitivity of 79.49% and specificity of 90.67% was achieved with a cut-off of 8 mL as ovarian volume. A cut-off value of 9 follicles to distinguish between PCOS and control women yielded a sensitivity of 82.35% and specificity of 92.0% while as a follicular size of 5 mm yielded sensitivity and specificity of 74.67% and 78.15% respectively. With all the three parameters sensitivity was 87.39% and specificity 87.84% with 92.04% PPV and 81.25% NPV. CONCLUSION: Using two or three sonographic criteria in combination improves sensitivity and helps diagnose additional patients with PCOS. Our results are at variance with the established cut-off values highlighting the fact that American Society for Reproductive Medicine consensus cut-off values are not reproducible in Indian context. |
format | Online Article Text |
id | pubmed-3987267 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-39872672014-04-16 Comparative evaluation of sonographic ovarian morphology of Indian women with polycystic ovary syndrome versus those of normal women Ahmed, Sanjeed Pahwa, Shivani Das, Chandan Jyoti Mir, Farooq A Nisar, Sobia Jehangir, Majid Parveen, Shameem Rashid, Aafia Ganie, Mohd Ashraf Indian J Endocrinol Metab Original Article OBJECTIVES: To study ovarian morphology by ultrasound in women with or without polycystic ovary syndrome (PCOS) and to establish cut-off values of these parameters in Indian women with PCOS. MATERIALS AND METHODS: A total of 119 consecutive women diagnosed PCOS and 77 apparently healthy women were enrolled. Transabdominal ultrasound examination was carried out to assess ovarian volume, stromal echogenecity, follicle number and size. Cut-off values of the above ovarian parameters with sensitivity, specificity, positive predictive value (PPV) and negative predictive values (NPV) were calculated. RESULTS: Sensitivity of 79.49% and specificity of 90.67% was achieved with a cut-off of 8 mL as ovarian volume. A cut-off value of 9 follicles to distinguish between PCOS and control women yielded a sensitivity of 82.35% and specificity of 92.0% while as a follicular size of 5 mm yielded sensitivity and specificity of 74.67% and 78.15% respectively. With all the three parameters sensitivity was 87.39% and specificity 87.84% with 92.04% PPV and 81.25% NPV. CONCLUSION: Using two or three sonographic criteria in combination improves sensitivity and helps diagnose additional patients with PCOS. Our results are at variance with the established cut-off values highlighting the fact that American Society for Reproductive Medicine consensus cut-off values are not reproducible in Indian context. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC3987267/ /pubmed/24741513 http://dx.doi.org/10.4103/2230-8210.129108 Text en Copyright: © Indian Journal of Endocrinology and Metabolism http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Ahmed, Sanjeed Pahwa, Shivani Das, Chandan Jyoti Mir, Farooq A Nisar, Sobia Jehangir, Majid Parveen, Shameem Rashid, Aafia Ganie, Mohd Ashraf Comparative evaluation of sonographic ovarian morphology of Indian women with polycystic ovary syndrome versus those of normal women |
title | Comparative evaluation of sonographic ovarian morphology of Indian women with polycystic ovary syndrome versus those of normal women |
title_full | Comparative evaluation of sonographic ovarian morphology of Indian women with polycystic ovary syndrome versus those of normal women |
title_fullStr | Comparative evaluation of sonographic ovarian morphology of Indian women with polycystic ovary syndrome versus those of normal women |
title_full_unstemmed | Comparative evaluation of sonographic ovarian morphology of Indian women with polycystic ovary syndrome versus those of normal women |
title_short | Comparative evaluation of sonographic ovarian morphology of Indian women with polycystic ovary syndrome versus those of normal women |
title_sort | comparative evaluation of sonographic ovarian morphology of indian women with polycystic ovary syndrome versus those of normal women |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3987267/ https://www.ncbi.nlm.nih.gov/pubmed/24741513 http://dx.doi.org/10.4103/2230-8210.129108 |
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