Fructose in obesity and cognitive decline: is it the fructose or the excess energy?

We read with interest the review by Lakhan and Kirchgessner, proposing that high fructose intake promotes obesity, metabolic syndrome, diabetes, and cognitive decline. Their focus on the role of fructose seems premature due to confounding from energy and the heavy reliance on low quality evidence fr...

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Autores principales: Chiavaroli, Laura, Ha, Vanessa, de Souza, Russell J, Kendall, Cyril WC, Sievenpiper, John L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3987663/
https://www.ncbi.nlm.nih.gov/pubmed/24666585
http://dx.doi.org/10.1186/1475-2891-13-27
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author Chiavaroli, Laura
Ha, Vanessa
de Souza, Russell J
Kendall, Cyril WC
Sievenpiper, John L
author_facet Chiavaroli, Laura
Ha, Vanessa
de Souza, Russell J
Kendall, Cyril WC
Sievenpiper, John L
author_sort Chiavaroli, Laura
collection PubMed
description We read with interest the review by Lakhan and Kirchgessner, proposing that high fructose intake promotes obesity, metabolic syndrome, diabetes, and cognitive decline. Their focus on the role of fructose seems premature due to confounding from energy and the heavy reliance on low quality evidence from animal models. There is a lack of high quality evidence directly assessing the role of fructose in cognitive decline. Although one cannot exclude the possibility of a link, it remains an unconfirmed hypothesis.
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spelling pubmed-39876632014-04-16 Fructose in obesity and cognitive decline: is it the fructose or the excess energy? Chiavaroli, Laura Ha, Vanessa de Souza, Russell J Kendall, Cyril WC Sievenpiper, John L Nutr J Letter to the Editor We read with interest the review by Lakhan and Kirchgessner, proposing that high fructose intake promotes obesity, metabolic syndrome, diabetes, and cognitive decline. Their focus on the role of fructose seems premature due to confounding from energy and the heavy reliance on low quality evidence from animal models. There is a lack of high quality evidence directly assessing the role of fructose in cognitive decline. Although one cannot exclude the possibility of a link, it remains an unconfirmed hypothesis. BioMed Central 2014-03-25 /pmc/articles/PMC3987663/ /pubmed/24666585 http://dx.doi.org/10.1186/1475-2891-13-27 Text en Copyright © 2014 Chiavaroli et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Letter to the Editor
Chiavaroli, Laura
Ha, Vanessa
de Souza, Russell J
Kendall, Cyril WC
Sievenpiper, John L
Fructose in obesity and cognitive decline: is it the fructose or the excess energy?
title Fructose in obesity and cognitive decline: is it the fructose or the excess energy?
title_full Fructose in obesity and cognitive decline: is it the fructose or the excess energy?
title_fullStr Fructose in obesity and cognitive decline: is it the fructose or the excess energy?
title_full_unstemmed Fructose in obesity and cognitive decline: is it the fructose or the excess energy?
title_short Fructose in obesity and cognitive decline: is it the fructose or the excess energy?
title_sort fructose in obesity and cognitive decline: is it the fructose or the excess energy?
topic Letter to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3987663/
https://www.ncbi.nlm.nih.gov/pubmed/24666585
http://dx.doi.org/10.1186/1475-2891-13-27
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