HEPBURN - investigating the efficacy and safety of nebulized heparin versus placebo in burn patients with inhalation trauma: study protocol for a multi-center randomized controlled trial

BACKGROUND: Pulmonary coagulopathy is a hallmark of lung injury following inhalation trauma. Locally applied heparin attenuates lung injury in animal models of smoke inhalation. Whether local treatment with heparin benefits patients with inhalation trauma is uncertain. The present trial aims at comp...

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Detalles Bibliográficos
Autores principales: Glas, Gerie J, Muller, Johannes, Binnekade, Jan M, Cleffken, Berry, Colpaert, Kirsten, Dixon, Barry, Juffermans, Nicole P, Knape, Paul, Levi, Marcel M, Loef, Bert G, Mackie, David P, Malbrain, Manu, Schultz, Marcus J, van der Sluijs, Koenraad F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3987885/
https://www.ncbi.nlm.nih.gov/pubmed/24661817
http://dx.doi.org/10.1186/1745-6215-15-91

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