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γδ T Cell and Other Immune Cells Crosstalk in Cellular Immunity

γδ T cells have been recognized as effectors with immunomodulatory functions in cellular immunity. These abilities enable them to interact with other immune cells, thus having the potential for treatment of various immune-mediated diseases with adoptive cell therapy. So far, the interactions between...

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Detalles Bibliográficos
Autores principales: He, Ying, Wu, Kangni, Hu, Yongxian, Sheng, Lixia, Tie, Ruxiu, Wang, Binsheng, Huang, He
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3987930/
https://www.ncbi.nlm.nih.gov/pubmed/24741636
http://dx.doi.org/10.1155/2014/960252
Descripción
Sumario:γδ T cells have been recognized as effectors with immunomodulatory functions in cellular immunity. These abilities enable them to interact with other immune cells, thus having the potential for treatment of various immune-mediated diseases with adoptive cell therapy. So far, the interactions between γδ T cell and other immune cells have not been well defined. Here we will discuss the interactivities among them and the perspective on γδ T cells for their use in immunotherapy could be imagined. The understanding of the crosstalk among the immune cells in immunopathology might be beneficial for the clinical application of γδ T cell.