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IL-27 Driven Upregulation of Surface HLA-E Expression on Monocytes Inhibits IFN-γ Release by Autologous NK Cells

HLA-G and HLA-E are HLA-Ib molecules with several immunoregulatory properties. Their cell surface expression can be modulated by different cytokines. Since IL-27 and IL-30 may either stimulate or regulate immune responses, we have here tested whether these cytokines may modulate HLA-G and -E express...

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Detalles Bibliográficos
Autores principales: Morandi, Fabio, Airoldi, Irma, Pistoia, Vito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3987937/
https://www.ncbi.nlm.nih.gov/pubmed/24741633
http://dx.doi.org/10.1155/2014/938561