Major and Minor Group Rhinoviruses Elicit Differential Signaling and Cytokine Responses as a Function of Receptor-Mediated Signal Transduction

Major- and minor-group human rhinoviruses (HRV) enter their host by binding to the cell surface molecules ICAM-1 and LDL-R, respectively, which are present on both macrophages and epithelial cells. Although epithelial cells are the primary site of productive HRV infection, previous studies have impl...

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Detalles Bibliográficos
Autores principales: Schuler, Bryce A., Schreiber, Michael T., Li, LuYuan, Mokry, Michal, Kingdon, Megan L., Raugi, Dana N., Smith, Cosonya, Hameister, Chelsea, Racaniello, Vincent R., Hall, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988043/
https://www.ncbi.nlm.nih.gov/pubmed/24736642
http://dx.doi.org/10.1371/journal.pone.0093897

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