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Long-Read Sequencing of Chicken Transcripts and Identification of New Transcript Isoforms
The chicken has long served as an important model organism in many fields, and continues to aid our understanding of animal development. Functional genomics studies aimed at probing the mechanisms that regulate development require high-quality genomes and transcript annotations. The quality of these...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988055/ https://www.ncbi.nlm.nih.gov/pubmed/24736250 http://dx.doi.org/10.1371/journal.pone.0094650 |
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author | Thomas, Sean Underwood, Jason G. Tseng, Elizabeth Holloway, Alisha K. |
author_facet | Thomas, Sean Underwood, Jason G. Tseng, Elizabeth Holloway, Alisha K. |
author_sort | Thomas, Sean |
collection | PubMed |
description | The chicken has long served as an important model organism in many fields, and continues to aid our understanding of animal development. Functional genomics studies aimed at probing the mechanisms that regulate development require high-quality genomes and transcript annotations. The quality of these resources has improved dramatically over the last several years, but many isoforms and genes have yet to be identified. We hope to contribute to the process of improving these resources with the data presented here: a set of long cDNA sequencing reads, and a curated set of new genes and transcript isoforms not currently represented in the most up-to-date genome annotation currently available to the community of researchers who rely on the chicken genome. |
format | Online Article Text |
id | pubmed-3988055 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-39880552014-04-21 Long-Read Sequencing of Chicken Transcripts and Identification of New Transcript Isoforms Thomas, Sean Underwood, Jason G. Tseng, Elizabeth Holloway, Alisha K. PLoS One Research Article The chicken has long served as an important model organism in many fields, and continues to aid our understanding of animal development. Functional genomics studies aimed at probing the mechanisms that regulate development require high-quality genomes and transcript annotations. The quality of these resources has improved dramatically over the last several years, but many isoforms and genes have yet to be identified. We hope to contribute to the process of improving these resources with the data presented here: a set of long cDNA sequencing reads, and a curated set of new genes and transcript isoforms not currently represented in the most up-to-date genome annotation currently available to the community of researchers who rely on the chicken genome. Public Library of Science 2014-04-15 /pmc/articles/PMC3988055/ /pubmed/24736250 http://dx.doi.org/10.1371/journal.pone.0094650 Text en © 2014 Thomas et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Research Article Thomas, Sean Underwood, Jason G. Tseng, Elizabeth Holloway, Alisha K. Long-Read Sequencing of Chicken Transcripts and Identification of New Transcript Isoforms |
title | Long-Read Sequencing of Chicken Transcripts and Identification of New Transcript Isoforms |
title_full | Long-Read Sequencing of Chicken Transcripts and Identification of New Transcript Isoforms |
title_fullStr | Long-Read Sequencing of Chicken Transcripts and Identification of New Transcript Isoforms |
title_full_unstemmed | Long-Read Sequencing of Chicken Transcripts and Identification of New Transcript Isoforms |
title_short | Long-Read Sequencing of Chicken Transcripts and Identification of New Transcript Isoforms |
title_sort | long-read sequencing of chicken transcripts and identification of new transcript isoforms |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988055/ https://www.ncbi.nlm.nih.gov/pubmed/24736250 http://dx.doi.org/10.1371/journal.pone.0094650 |
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