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Automated Protein Turnover Calculations from (15)N Partial Metabolic Labeling LC/MS Shotgun Proteomics Data
Protein turnover is a well-controlled process in which polypeptides are constantly being degraded and subsequently replaced with newly synthesized copies. Extraction of composite spectral envelopes from complex LC/MS shotgun proteomics data can be a challenging task, due to the inherent complexity o...
Autores principales: | Lyon, David, Castillejo, Maria Angeles, Staudinger, Christiana, Weckwerth, Wolfram, Wienkoop, Stefanie, Egelhofer, Volker |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988089/ https://www.ncbi.nlm.nih.gov/pubmed/24736476 http://dx.doi.org/10.1371/journal.pone.0094692 |
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