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Automated Protein Turnover Calculations from (15)N Partial Metabolic Labeling LC/MS Shotgun Proteomics Data

Protein turnover is a well-controlled process in which polypeptides are constantly being degraded and subsequently replaced with newly synthesized copies. Extraction of composite spectral envelopes from complex LC/MS shotgun proteomics data can be a challenging task, due to the inherent complexity o...

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Detalles Bibliográficos
Autores principales: Lyon, David, Castillejo, Maria Angeles, Staudinger, Christiana, Weckwerth, Wolfram, Wienkoop, Stefanie, Egelhofer, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988089/
https://www.ncbi.nlm.nih.gov/pubmed/24736476
http://dx.doi.org/10.1371/journal.pone.0094692

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