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Cortisol Biosynthesis in the Human Ocular Surface Innate Immune Response

Innate immune responses have a critical role in regulating sight-threatening ocular surface (OcS) inflammation. While glucocorticoids (GCs) are frequently used to limit tissue damage, the role of intracrine GC (cortisol) bioavailability via 11-beta-hydroxysteroid dehydrogenase type 1 (11β-HSD1) in O...

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Detalles Bibliográficos
Autores principales:	Susarla, Radhika, Liu, Lei, Walker, Elizabeth A., Bujalska, Iwona J., Alsalem, Jawaher, Williams, Geraint P., Sreekantam, Sreekanth, Taylor, Angela E., Tallouzi, Mohammad, Southworth, H. Susan, Murray, Philip I., Wallace, Graham R., Rauz, Saaeha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988113/ https://www.ncbi.nlm.nih.gov/pubmed/24736562 http://dx.doi.org/10.1371/journal.pone.0094913

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