Distant Homology Modeling of LCAT and Its Validation through In Silico Targeting and In Vitro and In Vivo Assays

LCAT (lecithin:cholesterol acyltransferase) catalyzes the transacylation of a fatty acid of lecithin to cholesterol, generating a cholesteryl ester and lysolecithin. The knowledge of LCAT atomic structure and the identification of the amino acids relevant in controlling its structure and function ar...

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Detalles Bibliográficos
Autores principales: Sensi, Cristina, Simonelli, Sara, Zanotti, Ilaria, Tedeschi, Gabriella, Lusardi, Giulia, Franceschini, Guido, Calabresi, Laura, Eberini, Ivano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988154/
https://www.ncbi.nlm.nih.gov/pubmed/24736652
http://dx.doi.org/10.1371/journal.pone.0095044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988154/
https://www.ncbi.nlm.nih.gov/pubmed/24736652
http://dx.doi.org/10.1371/journal.pone.0095044

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