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Virally mediated optogenetic excitation and inhibition of pain in freely moving non-transgenic mice

Primary nociceptors are the first neurons involved in the complex processing system that regulates normal and pathological pain(1). Our ability to excite and inhibit these neurons has been limited by pharmacological and electrical stimulation constraints; non-invasive excitation and inhibition of th...

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Detalles Bibliográficos
Autores principales: Iyer, Shrivats Mohan, Montgomery, Kate L., Towne, Chris, Lee, Soo Yeun, Ramakrishnan, Charu, Deisseroth, Karl, Delp, Scott L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988230/
https://www.ncbi.nlm.nih.gov/pubmed/24531797
http://dx.doi.org/10.1038/nbt.2834